| Parameter | Monitoring Parameters | Recommendations |
|---|---|---|
| Serum ferritin | 500-1000 mg/ml | Serum ferritin levels should be assessed every 3 months |
| Cardiac MRI T2* | >30 ms | Cardiac function and iron should be monitored by MRI T2* every 1 to 2 years for T2* > 20 ms or every 6 months for T2* < 10 ms. |
| Liver iron concentration (LIC) | <5000 μg/g dry weight | LIC should be determined by validated MRI technique after ~10-20 transfusions and every 6 –24 months. |