ParameterMonitoring ParametersRecommendations
Serum ferritin 500-1000 mg/ml Serum ferritin levels should be assessed every 3 months
Cardiac MRI T2* >30 ms Cardiac function and iron should be monitored by MRI T2* every 1 to 2 years for T2* > 20 ms or every 6 months for T2* < 10 ms.
Liver iron concentration (LIC) <5000 μg/g dry weight LIC should be determined by validated MRI technique after ~10-20 transfusions and every 6 –24 months.
Adapted from Consensus Statement of Clinical Care of Patients with Thalassemia in Canada
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