As iron continues to build up in the body, complications happen more often.

Transfused people with sickle cell disease and iron overload had higher rates of:

Death Stats 64%
(64% vs. 5% for people without iron overload) 
Organ failure
Organ failure
(71% vs. 19% for people without iron overload)
Pain episodes
Pain episodes 
(64% vs. 38% for people without iron overload)
N=35; defined as serum ferritin levels >1500 ng/mL and transferrin saturation >50%

Consider your kidneys!

Kidney complications are common in the general population of people with sickle cell disease. Regular monitoring can help ensure optimal care.

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